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application of a novel topical 2 povidoneiodine solution

  • A Novel Topical 2% Povidone-Iodine Solution for the ...

    Methods: Twenty-one patients aged 8 years and older were enrolled in this single-center, randomized, double-blind, vehicle-controlled Phase II clinical trial to assess the efficacy, safety and tolerability of twice-daily application of a novel 2% topical povidone-iodine solution in a dimethyl sulfoxide vehicle for 12 weeks duration. Patients were block randomized into two groups consisting of 14 patients in the active …

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  • A Novel Topical 2% Povidone–Iodine Solution for the ...

    2017-4-10 · application of a novel 2% topical povidone–iodine solution in a dimethyl sulfoxide vehicle for 12 weeks duration. Patients were block randomized into two groups consisting of 14 patients in the active arm and 7 patients in the vehicle only arm. All patients were evaluated at baseline, week 4, 8 and 12 and the results compared for overall

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  • A Novel Topical 2% Povidone-Iodine Solution for the ...

    2015-11-3 · Twenty-one patients aged 8 years and older were enrolled in this single-center, randomized, double-blind, vehicle-controlled Phase II clinical trial to assess the efficacy, safety and tolerability of twice-daily application of a novel 2% topical povidone-iodine solution in a dimethyl sulfoxide …

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  • A Novel Topical 2% Povidone–Iodine Solution for the ...

    2015-11-3 · Twenty-one patients aged 8 years and older were enrolled in this single-center, randomized, double-blind, vehicle-controlled Phase II clinical trial to assess the efficacy, safety and tolerability of twice-daily application of a novel 2% topical povidone–iodine solution in …

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  • A Novel Topical 2% Povidone-Iodine Solution for the ...

    2016-1-1 · We describe here the results of a small, randomized, double-blind, vehicle-controlled Phase II clinical trial with a novel topical agent for the treatment of common warts.Twenty-one patients aged 8 years and older were enrolled in this single-center, randomized, double-blind, vehicle-controlled Phase II clinical trial to assess the efficacy, safety and tolerability of twice-daily application of a novel 2% topical povidone-iodine solution in a dimethyl sulfoxide …

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  • A Novel Topical 2% Povidone–Iodine Solution for the ...

    2015-11-3 · Though application of a novel 2% topical many remedies exist, there is no consensus povidone–iodine solution in a dimethyl therapy backed by randomized-controlled sulfoxide vehicle for 12 weeks duration. clinical trials that are FDA approved for the Patients were block randomized into two groups consisting of 14 patients in the active arm and ...

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  • A Novel Topical 2% Povidone–Iodine Solution for the ...

    2015-11-3 · The most commonly used iodophor is povidone–iodine. Povidone–iodine kills microorganisms including bacteria, viruses, yeasts, molds, fungi and protozoa [7, 8]. In this randomized, double-blind, vehicle-controlled study, we utilized a novel 2% PVP-I solution in a topical dimethyl sulfoxide vehicle twice daily for the treatment of common warts.

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  • [PDF] Commentary: A Novel Topical 2% Povidone

    In “A Novel Topical 2% Povidone-Iodine Solution for the Treatment of Common Warts: A Randomized, Double-Blind, Vehicle-Controlled Trial,” twenty-one patients aged 8 years and older were enrolled in Phase II clinical trial to assess the efficacy, safety, and tolerability of twice-daily application of a novel 2% topical povidone–iodine solution in a dimethyl sulfoxide vehicle for 12 weeks duration1.

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  • Topical adelmidrol 2% emulsion, a novel aliamide, in

    Based on these considerations, a pilot study aimed to assess the efficacy and safety of twice daily application of a topical emulsion containing adelmidrol 2%, a novel aliamide, in a series of 20 patients (11 male and 9 female, mean age 8 (range 3-16) years) affected by mild AD was performed.

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  • Topical application of a novel, water-soluble γ

    2005-7-1 · Topical pre-or post-application of a 5% (93 mM) γ-TDMG solution in water propylene glycol/ethanol (2:1:2) significantly prevented sunburn cell formation, lipid peroxidation and edema/inflammation that were induced by exposure to a single dose of UV irradiation of 5 kJ/m 2 (290-380 nm, maximum 312 nm).

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  • Novel Topical Application of a Postbiotic, LactoSporin ...

    2020-9-15 · cosmetics Article Novel Topical Application of a Postbiotic, LactoSporinfi, in Mild to Moderate Acne: A Randomized, Comparative Clinical Study to Evaluate its E cacy, Tolerability and Safety y Muhammed Majeed 1,2,3, Shaheen Majeed 1,2,3, Kalyanam Nagabhushanam 2, Lakshmi Mundkur 1, H. R. Rajalakshmi 3, Kalpesh Shah 3,* and Kirankumar Beede 1 1 Sami Labs Limited, 19/1 & 19/2, …

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  • Topical Application of a Novel, Water‐soluble

    2007-4-30 · We investigated whether the topical application of a novel, water‐soluble γ‐tocopherol (γ‐Toc) derivative, γ‐tocopherol‐N,N‐dimethylglycinate hydrochloride (γ‐TDMG), could protect against UV‐induced skin damage in hairless mice.Topical pre‐or post‐application of a 5% (93 mM) γ‐TDMG solution in water/propylene glycol/ethanol (2:1:2) significantly prevented sunburn ...

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  • Topical cutaneous CO2 application by means of a

    Background: We previously demonstrated that topical cutaneous application of CO2, by means of a hydrogel in which the CO2 readily dissolves, increases blood flow and oxygen dissociation from hemoglobin in the soft tissues surrounding bone. In the present study, we utilized a rat fracture model to test the hypothesis that application of this treatment to fractured limbs would accelerate ...

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  • A randomized phase 2 trial of the efficacy and safety

    2019-6-26 · This is the first randomized phase 2 trial for CAP that is comparing topical PVP-I 1% and 2% nail solution to vehicle-control. Materials and methods This was a multicenter, prospective, randomized, double-blind, vehicle-controlled, phase 2 study of adult patients with cancer who developed acute paronychia associated with cancer therapy.

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  • Topical application of a novel, water-soluble γ

    2005-7-1 · Topical pre-or post-application of a 5% (93 mM) γ-TDMG solution in water propylene glycol/ethanol (2:1:2) significantly prevented sunburn cell formation, lipid peroxidation and edema/inflammation that were induced by exposure to a single dose of UV irradiation of 5 kJ/m 2 (290-380 nm, maximum 312 nm).

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  • Stratum corneum pharmacokinetics of the anti-fungal

    Stratum corneum pharmacokinetics of the anti-fungal drug, terbinafine, in a novel topical formulation, for single-dose application in dermatophytoses Curr Med Res Opin . 2007 Jun;23(6):1293-302. doi: 10.1185/030079907X199664.

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  • International www.clinpharmacol.com Journal of

    2015-12-17 · Effects of a novel finasteride 0.25% topical solution on scalp and serum dihydrotestosterone in healthy men with ... For each application, 1 mL (i.e., 2.275 mg finasteride) of the solu-

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  • A novel finasteride 0.25% topical solution for ...

    2014-4-29 · A novel finasteride 0.25% topical solution for androgenetic alopecia: pharmacokinetics and ... (1 mL (2.275 mg)/application). Reference formulation (1 mg tablet) was orally administered o.d. for

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  • Efficacy and safety of tavaborole topical solution, 5%,

    2015-7-1 · Tavaborole topical solution, 5% (Anacor Pharmaceuticals, Inc, Palo Alto, CA) is a novel, boron-based pharmaceutical approved by the Food and Drug Administration (FDA) in July 2014 for the treatment of toenail onychomycosis caused by Trichophyton rubrum and T mentagrophytes. 1 Tavaborole represents a new class of pharmaceutical antifungal agents with a novel chemical structure and …

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  • Ocular Pharmacokinetics of a Topical Ophthalmic ...

    2019-1-7 · Cequa®, a unique and first-in-class preservative free cyclosporine-A (CsA) nanomicellar topical formulation was recently approved by US FDA for treatment of dry eye disease or keratoconjuntivitis sicca (KCS). Being highly hydrophobic, CsA is currently available as an oil based emulsion, which has its own shortcomings. Developing an aqueous and clear formulation of CsA is …

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  • Cosmetics | Free Full-Text | Novel Topical Application

    Acne vulgaris is a common skin disorder of pilosebaceous units. The therapy for mild-to-moderate acne includes topical antibiotics, benzoyl peroxide and retinoids. In this open-label, randomized monocentric study, we compared the efficacy of LactoSporin® 2% w/w cream with benzoyl peroxide in 64 male and female subjects with mild-to-moderate acne for three weeks.

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  • Povidone-iodine solution as SARS-CoV-2 prophylaxis

    2020-10-27 · The safety profile of topical application of PVP-I to oral mucosa has been demonstrated. As health care settings develop new protocols around SARS-CoV-2 prophylaxis, the application of PVP-I solutions to the upper aerodigestive tract appears to be a low-cost and simple intervention for reducing viral burden from relevant mucosal surfaces.

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  • Topical Application of a Novel, Hydrophilic γ-Tocopherol ...

    2015-10-22 · directly inhibits COX-2 activity, all of which likely play a role in mediating its suppressive effects on photo-inflammation. Our data further suggest that the topical application of g-TDMG, a novel hydrophilic g-Toc derivative, may be efficacious in preventing and reducing UV …

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  • Topical Application of A Novel Immunomodulatory

    2005-9-1 · Topical treatment with RDP58 (10 and 2 mg per mL), or a positive control corticosteroid, 0.05% betamethasone, 30 min following TPA application reduces the increases in dorsal skin thickness (A) and weight (B) as well as ear thickening (C), whereas water-vehicle alone has no effect. Thickness measurements were made using digital calipers and ...

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  • Topical Application of a Novel, Water-soluble γ

    2004-9-2 · We investigated whether the topical application of a novel, water-soluble γ-tocopherol (γ-Toc) derivative, γ-tocopherol-N,N-dimethylglycinate hydrochloride (γ-TDMG), could protect against UV-induced skin damage in hairless mice.Topical pre- or post-application of a 5% (93 mM) γ-TDMG solution in water/propylene glycol/ethanol (2:1:2) significantly prevented sunburn cell formation, lipid ...

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  • In Vitro Evaluation of Novel Phenytoin-Loaded Alkyd ...

    In Vitro Evaluation of Novel Phenytoin-Loaded Alkyd Nanoemulsions Designed for Application in Topical Wound Healing. Teo SY(1), Yew MY(2), Lee SY(3), Rathbone MJ(4), Gan SN(5), Coombes AGA(6). Author information: (1)School of Postgraduate Studies and Research, International Medical University, Kuala Lumpur, Malaysia.

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  • Efficacy and safety of a novel topical agent for

    2019-6-10 · Although methyl-tertiary butyl ether (MTBE) is the only clinical topical agent for gallstone dissolution, its use is limited by its side effects mostly arising from a relatively low boiling point (55 °C). In this study, we developed the gallstone-dissolving compound containing an aromatic moiety, named 2-methoxy-6-methylpyridine (MMP) with higher boiling point (156 °C), and compared its ...

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  • Combination of a dual 5

    Topical application of a 0.2% solution of hydrocortisone valerate alone inhibited phorbol ester-induced mouse skin inflammation by 92%. A 1% solution of BMY 30094 alone or a low dose of hydrocortisone valerate (0.005%) had no significant effect on the inflammatory reaction.

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  • Evaluating the novel application of cyclosporine 0.1%

    Expert opinion: Topical cyclosporine A 0.1% represents a promising, novel medication for the management of DED, Meibomian gland dysfunction, and inflammatory OSD. It is primarily beneficial for those patients requiring topical immunomodulatory therapy. This topical formulation also has the potential to meaningfully improve the management of ...

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  • Complete Wound Closure Following a Single Topical ...

    demonstrated AHSC may be a viable single application topical intervention for DFUs and warrants investigation in larger, controlled studies. KEYWORDS autologous homologous skin construct, diabetic foot ulcer, novel therapy, wound healing Received: 2 March 2020 Revised: 23 April 2020 Accepted: 26 April 2020 DOI: 10.1111/iwj.13404

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  • Cosmetics | Free Full-Text | Novel Topical Application

    Acne vulgaris is a common skin disorder of pilosebaceous units. The therapy for mild-to-moderate acne includes topical antibiotics, benzoyl peroxide and retinoids. In this open-label, randomized monocentric study, we compared the efficacy of LactoSporin® 2% w/w cream with benzoyl peroxide in 64 male and female subjects with mild-to-moderate acne for three weeks.

    Get Price
  • Topical application of a novel, water-soluble gamma ...

    2005-7-1 · Topical pre- or post-application of a 5% (93 mM) gamma-TDMG solution in water/propylene glycol/ethanol (2:1:2) significantly prevented sunburn cell formation, lipid peroxidation and edema/inflammation that were induced by exposure to a single dose of UV irradiation of 5 kJ/m2 (290-380 nm, maximum 312 nm).

    Get Price
  • Targeting Reactive Oxygen Species Production as a

    2020-6-19 · Currently topical solutions of NAC are already used in ophthalmology for application in keratoconjunctivitis sicca (using 20% weight/volume solution or 10%), meibomian gland dysfunction (using 5%) and Sjögren's dry eye syndrome (also using 5%). This is a single center, double-blind, placebo-controlled, randomized trial.

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  • Treatment data using a topical povidone-iodine

    2019-4-1 · The standard treatment of cutaneous abscesses in the emergency department is incision and drainage (I&D). The purpose of this investigation is to determine the feasibility of using a povodine-iodine topical antiseptic solution (PVP-I) as a clinical adjunct in the treatment of superficial skin abscesses after I&D, and the data is related to “Pilot Study to Evaluate the Adjunct Use of a ...

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  • International www.clinpharmacol.com Journal of

    2015-12-17 · Effects of a novel finasteride 0.25% topical solution on scalp and serum dihydrotestosterone in healthy men with ... For each application, 1 mL (i.e., 2.275 mg finasteride) of the solu-

    Get Price
  • RESEARCH ARTICLE Nanomiemgel - A Novel Drug

    a novel carrier system for the topical application of aceclofenac (ACE) and ... A Novel Drug Delivery System for Topical Application ... were added to 2 mL of acetone. When a clear solution was ...

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  • In Vitro Release Testing (IVRT) of Topical Hydrocortisone ...

    2020-3-24 · In Vitro Release Testing (IVRT) of Topical Hydrocortisone Acetate Creams: A Novel Approach Using Positive and Negative Controls Nyengeterai Amanda Mudyahoto1, Seeprarani Rath1, Ashmita Ramanah1, and Isadore Kanfer1,2* 1Division of Pharmaceutics, Faculty of Pharmacy, Rhodes University, Grahamstown, South Africa.

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  • Comparative Study to Evaluate Tolerability of Topical

    2020-4-10 · Patients with androgenetic alopecia treated with alcohol-based minoxidil topical solutions often report local irritation, dryness, and redness of the scalp. We evaluate the in-use tolerance of 5% minoxidil novel formulation topical solution—test product (TP)—compared with 5% minoxidil alcohol-based topical solutions—reference product 1 (RP1) and reference product 2 (RP2)—in Indian men ...

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  • (PDF) Efficacy and safety of tavaborole topical solution ...

    Conclusion: Tavaborole demonstrates a favorable benefit-risk profile in treatment of toenail onychomycosis. ( J Am Acad Dermatol 2015;73:62-9.)Key words: antifungal agents; arthrodermataceae; nails; onychomycosis; randomized controlled trial; tavaborole.Tavaborole topical solution, 5% (Anacor Pharmaceuticals, Inc, Palo Alto, CA) is a novel, boron-based pharmaceutical approved by the Food …

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  • Topical Adelmidrol 2% Emulsion, a Novel Aliamide, in the ...

    the efficacy and safety of twice daily application of a topical emulsion containing adelmidrol 2%, a novel aliamide, in a series of 20 patients (11 male and 9 female, mean age 8 (range 3-16) years) affected by mild AD was performed. Complete resolution with no side effects was observed

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  • Topical Application of A Novel Immunomodulatory

    2015-10-23 · Topical Application of A Novel Immunomodulatory Peptide, RDP58, Reduces Skin Inflammation in the Phorbol Ester-Induced Dermatitis Model ChristopherG.DeVry,MarybethValdez,MirellaLazarov, Evelyn Muhr, Roland Buelow, Timothy Fong, and Suhasini Iyer Department Discovery Research, Sangstat Medical Corporation, Fremont, California, USA

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  • DailyMed - APOTHECARY PVP TOPICAL- povidone

    2019-1-1 · A novel topical minocycline foam for the treatment of moderate-to-severe acne vulgaris: Results of 2 randomized, double-blind, phase 3 studies Author links open overlay panel Linda Stein Gold MD a Sunil Dhawan MD b Jonathan Weiss MD c Zoe Diana Draelos MD d …

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  • A novel topical minocycline foam for the treatment of ...

    2015-7-1 · A total of 50 cases were analyzed, 68% (34/50) of which were female and 32% (16/50) male, constituting a female/male ratio of 2.125 to 1. The age at the time of the patients’ first treatment ranged from 1 month to 18 months (5.010 ± 3.940 months).The surface area of the patients was 5.812 ± 3.128 cm 2 in average. A total of 47 patients (94%) started treatment at the age of less than one ...

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  • A novel topical nano-propranolol for treatment of ...

    2018-11-26 · Subjects were randomized to use either Topical Herbal Solution or Topical Minoxidil 5% for 36 weeks. To our knowledge, this herbal solution for the first time covers all four major causes of AGA, including the 5α-reductase enzyme, androgen receptors, paracrine agents that affecting dermal papilla and hair cell apoptosis processes.

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  • Evaluating the Topical Herbal Solution on the

    principal display panel. NDC 11673-003-34 - Compare to active ingredinet in Betadine* Povidone iodine 10% topical solution - first aid antiseptic - kills germs in minor burns, cuts and scrapes - up & up - 8 FL OZ (236 mL) NDC 11673-003-34. Compare to active ingredinet in Betadine*.

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  • DailyMed - FIRST AID ANTISEPTIC- povidone-iodine

    Rebamipide ophthalmic solution is a mucin secretagogue which is an important therapeutic agent in the treatment of dry eye. It has been noted that dry eye in office workers is associated with a decrease in secretory mucin. This study aimed to evaluate the effects of 2% rebamipide ophthalmic solution in mice subjected to environmental dry eye stress (EDES), which mimics the conditions of office ...

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  • The Effects of Rebamipide 2% Ophthalmic Solution ...

    2020-3-26 · Eccrine hidrocystomas are uncommon cystic lesions that develop benign tumors in sweat glands, mostly in the malar, periorbital, chest, axilla, and neck areas. Ranging from 1 to 6 mm in diameter, they typically present in adults, with a predominance for women.1 They can enlarge in hot conditions and their treatment may be especially challenging.2 We report a case of multiple eccrine ...

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  • Therapeutic treatment of multiple eccrine

    2018-11-20 · Topical anesthetic ( lidocaine-Prilocaine) Cream application Before speculum Examination In Postmenopausal Women. The Journal of Minimally Invasive Gynecology . 2012. 19:350-355. The efficiency and Safety of Intrarectal,Topical anesthesia for Transrectal ultrasound- guided Prostate Biopsy: A systematic Review and Meta-analysis.

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  • Povidone-iodine solution as SARS-CoV-2 prophylaxis

    2020-10-27 · The safety profile of topical application of PVP-I to oral mucosa has been demonstrated. As health care settings develop new protocols around SARS-CoV-2 prophylaxis, the application of PVP-I solutions to the upper aerodigestive tract appears to be a low-cost and simple intervention for reducing viral burden from relevant mucosal surfaces.

    Get Price
  • Topical Cutaneous CO2 Application by Means of a Novel ...

    2019-3-11 · Conclusions: Topical cutaneous application of CO 2 by means of a hydrogel accelerated fracture repair in association with the promotion of angiogenesis, blood flow, and endochondral ossification. Clinical Relevance: Topical cutaneous application of CO 2 by this method is a novel and potentially useful therapy for accelerating fracture repair. A

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  • Prophylaxis of Endophthalmitis with Topical Povidone ...

    1991-12-1 · A significantly lower incidence of culture-positive endophthalmitis (P < 0.03) was observed in the operating rooms using povidoneiodine (2 of 3489 or 0.06%) compared with those using silver protein solution (11 of 4594 or 0.24%). Use of topical povidone-iodine in over 3000 cases was not associated with any adverse reactions.

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  • Evaluating the Topical Herbal Solution on the

    2018-11-26 · Subjects were randomized to use either Topical Herbal Solution or Topical Minoxidil 5% for 36 weeks. To our knowledge, this herbal solution for the first time covers all four major causes of AGA, including the 5α-reductase enzyme, androgen receptors, paracrine agents that affecting dermal papilla and hair cell apoptosis processes.

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  • A Review on Ocular Novel Drug Delivery Systems of ...

    day.6-8 Unfortunately, topical dosage forms face some challenges, like low drug penetration to the different layers of the eye, high frequency of administration, low residence time, and systemic toxicities caused by long-term use.9,10 Recently, many efforts have been made to improve topical ocular drug delivery by designing various novel

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  • Tavaborole 5% Solution: A Novel Topical Treatment

    2015-12-1 · Tavaborole: A Novel Topical Antifungal. Tavaborole 5% solution (Kerydin ®) was approved by the US FDA for treatment of onychomycosis in July 2014. Tavaborole is the first in a new class of boron atom-containing drugs, the oxaboroles. Tavaborole’s mechanism of action is …

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  • Topical Finasteride + Minoxidil | Hair Loss | Bauman

    2017-3-28 · The objective of the present study was to develop and optimize generic topical gel formulation of diclofenac sodium through quality by design approaches. The quality target product profile was set for the critical quality attributes of the gel. The key material variables like hydrophilic gelling agent carbopol and penetration enhancer kolliphor were optimized using design of experiments.

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  • iodine for warts| iodine warts| Commentary: A Novel ...

    A Novel Topical 2% Povidone-Iodine Solution for the Treatment of Common Warts: A Randomized, Double-Blind, Vehicle-Controlled Trial,” twenty-one patients aged 8 years and older were enrolled in Phase II clinical trial to assess the efficacy, safety, and tolerability of twice-daily application of a novel 2% topical povidone–iodine solution in a dimethyl sulfoxide vehicle for 12 weeks duration

    Get Price
  • Targeting Reactive Oxygen Species Production as a

    2020-6-19 · Currently topical solutions of NAC are already used in ophthalmology for application in keratoconjunctivitis sicca (using 20% weight/volume solution or 10%), meibomian gland dysfunction (using 5%) and Sjögren's dry eye syndrome (also using 5%). This is a single center, double-blind, placebo-controlled, randomized trial.

    Get Price
  • Topical Application of a Novel, Water-soluble γ

    2004-9-2 · We investigated whether the topical application of a novel, water-soluble γ-tocopherol (γ-Toc) derivative, γ-tocopherol-N,N-dimethylglycinate hydrochloride (γ-TDMG), could protect against UV-induced skin damage in hairless mice. Topical pre- or post-application of a 5% (93 mM) γ-TDMG solution in water/propylene glycol/ethanol (2:1:2) significantly prevented sunburn cell formation, lipid ...

    Get Price
  • Topical application of a novel, water-soluble γ

    2005-7-1 · Topical pre-or post-application of a 5% (93 mM) γ-TDMG solution in water propylene glycol/ethanol (2:1:2) significantly prevented sunburn cell formation, lipid peroxidation and edema/inflammation that were induced by exposure to a single dose of UV irradiation

    Get Price
  • Application of Topical Immunotherapy in the

    2021-3-23 · Squaric Acid Dibutylester. SADBE or 3,4-dibutoxycyclobut-3-ene-1,2-dione is a sensitizing agent with chemical structure C 12 H 18 O 4 ().Its efficacy in AA treatment was first reported in 1980. 66 SADBE is an ideal sensitizing agent due to its absence in the environment and lack of cross-reaction with other agents. However, it is unstable in acetone solution and can degrade within a few hours ...

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  • Hydrogen Peroxide Trial to Investigate the Efficacy of

    2021-6-18 · 30% hydrogen peroxide liquid topical application. 2 drops (0.10 ml) of hydrogen peroxide solution per centimeter of lesion. Once every week for continuous 4 weeks. If there is complete clinical response, further hydrogen peroxide will not be done.

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  • Topical application of nitrosonifedipine, a novel

    Topical application of nitrosonifedipine, a novel radical scavenger, ameliorates ischemic skin flap necrosis in a mouse model Yutaka Fukunaga MD Department of Plastic and Reconstructive Surgery, Institute of Biomedical Sciences, Tokushima University Graduate School

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  • Current therapies of female androgenetiC alopeCia and

    2006-12-6 · hair cycle. In the case of AGA, topical application of minoxidil 2% or 5% solution is necessary twice a day over a longer period of time. The claimed mode of action of aminexil as an antifibrotic agent is to inhibit collagen formation around the hair follicle and to maintain the follicle survival. Aminexil’s primary claim is prevention

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  • Regeneration Booster Evaluation of a Novel Anti-aging

    2020-12-31 · ease of application were rated “positive” by 100% of study subjects. Photographic improvement was most notable in texture and lines on the cheeks and eye area. CONCLUSION Regeneration Booster when used as a stand–alone anti-aging solution delivers rapid and significant reduction in the visible signs of aging.

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  • US Patent Application for COMPOSITION OF A NOVEL

    2016-8-6 · Compositions of powder mosquito repellent formulations have been provided. It also describes the process to manufacture the same. The formulations contained synthetic and natural insect repellents. The compositions can also contain anti-allergic and anti-inflammatory components. The powder mosquito repellent can be applied on the skin or on the surrounding surfaces such as bed sheets, sleeping ...

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  • Topical Cutaneous CO 2 Application by Means of a

    2020-5-19 · Topical cutaneous application of CO 2 by means of a hydrogel accelerated fracture repair in association with the promotion of angiogenesis, blood flow, and endochondral ossification. Clinical Relevance: Topical cutaneous application of CO 2 by this method is a novel and potentially useful therapy for accelerating fracture repair.

    Get Price
  • Application and outlook of topical hemostatic

    Despite the various forms and functions of topical hemostatic materials that have been developed for different clinical conditions, uncontrolled hemorrhage still causes over 30% of trauma deaths across the world. Therefore, it is important to fabricate fast, efficient, safe, and ready-to-use novel …

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  • Nanomiemgel - A Novel Drug Delivery System for

    2014-12-29 · Also, imiquimod caused a pronounced increase (26.00±3.02 to 174.00±16.27 µm) in the ear thickness of the mice by the third day of topical application. However, NMG significantly (p<0.01) reduced the ear swelling by 3.22 and 2.01-fold more than FD and MKT, respectively.

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  • Synthesis and stability evaluation of novel

    2020-11-11 · Synthesis and stability evaluation of novel peptidomimetic Caspase-1 inhibitors for topical application Sandrine Chambon a, Sandrine Talano a, Corinne Millois a, Laurence Dumais a, Romain Pierre a, Loic Tomas a,Celine Mathieu a, Anne-Laurence Ghilini a, Nicolas Vanthuyne b, Kevin Reverse a, Anne Brethon c, Vincent Rodeschini c, Catherine Comino a,Gregoire Mouis a, Ghizlane El-Bazbouz …

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  • Novel topical foam promising for papulopustular

    Published results from two 12-week, vehicle-controlled phase 3 studies show that a novel topical foam formulation of minocycline 1.5% may be effective in reducing inflammatory lesions. Treatment with an oral tetracycline is commonly used for patients with moderate-to-severe papulopustular rosacea (PPR), and while it can be very effective for ...

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  • Topical application of endothelin receptor A

    2020-6-11 · Topical application of selective endothelin A receptor (ETAR) antagonist ambrisentan significantly attenuated the development of IMQ-induced psoriasiform dermatitis and also significantly ...

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  • Actikerall™ Topical Solution for Treatment of Actinic ...

    2016-5-1 · Actikerall™ is a transparent, colorless to slightly orange-white solution packaged in 25 mL glass bottles, accompanied by a nylon brush that allows for easy application. 5-FU-SA is recommended for application once daily to a total area of up to 25 cm 2, which may include the lesion(s) and a small area of surrounding skin (rim of healthy skin ...

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  • Development and Evaluation of a Human Skin Equivalent

    2021-6-20 · solution was magnetically stirred for at least 3 h to completely dissolve the pellets and to get a homogeneous solution. The solution was used within 3 h after the solution was ready. The prepared PCL solution was placed to in a 6-mL polypropylene syringe with a 18 G needle gauge of 1.20 mm. The feed rate of the polymer solution was 1 mL/h, which

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  • Figure 1 from Efficacy of Topical Combination of

    Fig. 1 Differences in hair density in both treatment groups at weeks 8 (p = 0.72), 16 (p = 0.86), and 24 (p = 0.66) - 'Efficacy of Topical Combination of 0.25% Finasteride and 3% Minoxidil Versus 3% Minoxidil Solution in Female Pattern Hair Loss: A Randomized, Double-Blind, Controlled Study'

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  • Study of Different Doses of a Novel Treatment for ...

    2008-5-19 · The intent is for all subjects to complete a 180 day treatment period consisting of 90 consecutive days of once daily treatment with their assigned study treatment followed by an additional 90 days of three times weekly dosing, even if the treated toenail(s) is evaluated as a 'complete responder' prior to the end of treatment 180 day treatment period.

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  • Almirall announces FDA approval of Klisyri®

    2020-12-15 · Klisyri® is a novel, topical first-in-class microtubule inhibitor that represents a significant step forward in the treatment of AK due to its short treatment protocol (once daily application for 5 days), and proven efficacy and safety profile. Actinic keratosis is the second most common diagnosis made by dermatologists in the United States 1.

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  • Foams as novel delivery vehicle for topical application

    2019-11-10 · Foams as novel delivery vehicle for topical application Dissertation submitted in fulfilment of the requirements for the degree of Doctor in Natural Science at the Christian Albrecht University, Kiel, Germany by Alexandra Arzhavitina Kiel 2009

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  • Actikerall™ Topical Solution for Treatment of Actinic ...

    2016-5-1 · Actikerall™ is a transparent, colorless to slightly orange-white solution packaged in 25 mL glass bottles, accompanied by a nylon brush that allows for easy application. 5-FU-SA is recommended for application once daily to a total area of up to 25 cm 2, which may include the lesion(s) and a small area of surrounding skin (rim of healthy skin ...

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  • Diclofenac Topical Patch, Gel and Solution

    2018-9-14 · Diclofenac sodium topical gel 1%, approved in October 2007 Diclofenac sodium topical solution 1.5% with dimethyl sulfoxide (DMSO, 45.5% w/w), approved in November 2009 Diclofenac sodium topical solution 2% with dimethyl sulfoxide (DMSO, 45.5% w/w), approved in January 2014 . Indication(s) Under Review in

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  • 4 patents for novel beauty product emulsifiers and

    2018-1-24 · An in-depth view of patents that show novel uses for emulsifiers and surfactants. 1. Stabilised, sprayable emulsion containing active agent particles. US Patent 9,700,510. Application No 15/173,849. Granted 11 July 2017. Assignee Mission Pharmacal Company. The patent describes an emulsion that includes a hydrofluoro-based propellant and active ...

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  • Single and multiple dose pharmacokinetics of a novel ...

    2018-7-13 · In Study 2, daily application of mirtazapine for 14 days resulted in mean T max = 2.1 hr, C max = 39.6 ng/mL, AUC 0-24 = 400 ng*hr/mL, AUC 0-∞ = 647 ng*hr/mL and calculated half-life = 20.7 hr. Single and repeat topical doses of a novel mirtazapine transdermal ointment achieve measurable plasma concentrations in cats.

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  • Role of topical peptides in preventing or treating aged ...

    2009-8-27 · Each treatment group received its solution after single application of 180 mJ cm −2 UVB treatment Silk protein significantly inhibited skin lesion formation and elevated expression of COX-2 protein more than BSA and vehicle: Zhaorigetu et al. Anti-ageing and anti-tumour: R, AC, PC

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  • Topical Application of TAT-Superoxide Dismutase in ...

    After 2-week treatments, the symptom score (total) was decreased from 6.9 to 3.0 with TTA group, from 7.1 to 6.7 with the placebo group, and from 7.1 to 6.9 with TTN group. Of all the three treatments, only topical application of TAT-SOD to acupoints LI 20 significantly improved AR symptom.

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  • Topical Application of Naltrexone to the Ocular

    2016-2-25 · Purpose: A short-term, randomized double-masked study was conducted to test the tolerability of topical application of naltrexone to the corneal surface. Methods: Healthy human volunteers were recruited at the Penn State Hershey Medical Center between 2010 and 2013. Study groups of 4 subjects were established to receive escalating dosages of naltrexone; within each group, 1 subject …

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  • Study of Different Doses of a Novel Treatment for ...

    2008-5-19 · The intent is for all subjects to complete a 180 day treatment period consisting of 90 consecutive days of once daily treatment with their assigned study treatment followed by an additional 90 days of three times weekly dosing, even if the treated toenail(s) is evaluated as a 'complete responder' prior to the end of treatment 180 day treatment period.

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  • Foams as novel delivery vehicle for topical application

    2019-11-10 · Foams as novel delivery vehicle for topical application Dissertation submitted in fulfilment of the requirements for the degree of Doctor in Natural Science at the Christian Albrecht University, Kiel, Germany by Alexandra Arzhavitina Kiel 2009

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  • ORIGINAL ARTICLE Topical Administration of Allogeneic ...

    2013-6-18 · The topical application of 1,000,000 MSCs on a collagen ... provides a novel therapeutic strategy for increasing wound clo- ... solution was isolated and purified as described previously (14). A collagen sponge was created by pipetting 500 mL of 3% (weight) type 1 bovine atelo-

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  • A Phase I Study of Topical Tempol for the Prevention

    Purpose: Complete alopecia is a universal complication of whole brain radiation therapy which contributes to patient anxiety over treatment. Tempol, a nitroxide radioprotector, has been shown to protect against radiation-induced alopecia in an animal model. This phase Ib study was designed to evaluate the safety and side effect profile of topical Tempol in patients with brain metastases being ...

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  • Role of topical peptides in preventing or treating aged ...

    2009-8-27 · Each treatment group received its solution after single application of 180 mJ cm −2 UVB treatment Silk protein significantly inhibited skin lesion formation and elevated expression of COX-2 protein more than BSA and vehicle: Zhaorigetu et al. Anti-ageing and anti-tumour: R, AC, PC

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  • Topical Application of Herbal Mixture Extract Inhibits ...

    In this study, we investigated the effect of topical application of KM110329 ethanol extract on the ovalbumin (OVA) or 2,4-dinitrochlorobenzene- (DNCB-) induced AD mouse models. For that purpose, we observed the effects of KM110329 on blood eosinophils, skin mast cells, production of serum IgE, and expression of cytokine mRNA in the atopic ...

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  • Diclofenac Topical Patch, Gel and Solution

    2018-9-14 · Diclofenac sodium topical gel 1%, approved in October 2007 Diclofenac sodium topical solution 1.5% with dimethyl sulfoxide (DMSO, 45.5% w/w), approved in November 2009 Diclofenac sodium topical solution 2% with dimethyl sulfoxide (DMSO, 45.5% w/w), approved in January 2014 . Indication(s) Under Review in

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  • Topical Application of Naltrexone to the Ocular

    2016-2-25 · Purpose: A short-term, randomized double-masked study was conducted to test the tolerability of topical application of naltrexone to the corneal surface. Methods: Healthy human volunteers were recruited at the Penn State Hershey Medical Center between 2010 and 2013. Study groups of 4 subjects were established to receive escalating dosages of naltrexone; within each group, 1 subject …

    Get Price
  • Topical Antifungals for Treatment of Onychomycosis -

    2016-11-1 · Elewski BE, et al. Efficacy and safety of tavaborole topical solution, 5%, a novel boron-based antifungal agent, for the treatment of toenail onychomycosis. J Am Acad Dermatol . 2015;73(1):62–69.

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  • Single and multiple dose pharmacokinetics of a novel ...

    2018-7-13 · In Study 2, daily application of mirtazapine for 14 days resulted in mean T max = 2.1 hr, C max = 39.6 ng/mL, AUC 0-24 = 400 ng*hr/mL, AUC 0-∞ = 647 ng*hr/mL and calculated half-life = 20.7 hr. Single and repeat topical doses of a novel mirtazapine transdermal ointment achieve measurable plasma concentrations in cats.

    Get Price