Extracellular Melanin in Inflammatory Middle Ear
The Fontana-Masson stain identifies melanin, by demonstrating an accumulation of black material wherever melanin granules have reduced silver nitrate to metallic silver. The Prussian blue stain identifies iron by a chemical reaction that takes place in the tissue producing a blue colored iron salt in situ. Melan-A is a melanocyte differentiation antigen, recognized by autologous cytotoxic T lymphocytes.
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