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efficacy of high-dose albendazole cost

  • Efficacy of High-Dose Albendazole with Ivermectin for ...

    Efficacy of High-Dose Albendazole with Ivermectin for Treating Imported Loiasis, Italy. We describe the outcomes of 16 cases of imported loiasis in Italy. Patients had microfilaremia <20,000/mL and were treated with high-dose albendazole for 28 days and a single dose of ivermectin. This combination might be an effective treatment option in ...

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  • Efficacy of High-Dose Albendazole With Ivermectin for ...

    Efficacy of High-Dose Albendazole With Ivermectin for Treating Imported Loiasis, Italy - PubMed. We describe the outcomes of 16 cases of imported loiasis in Italy. Patients had microfilaremia <20,000/mL and were treated with high-dose albendazole for 28 days and a single dose of ivermectin. This combination might be an effective treatment option in ...

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  • Efficacy of High-Dose Albendazole with Ivermectin for ...

    In conclusion, a combination of high-dose albendazole (400 mg 2×/d for 28 d) plus a single 200 µg/kg dose of ivermectin might be recommended for loiasis patients with microfilaremia <20,000/mL as an alternative to diethyl-carbamazine, which is the treatment of choice for loiasis but is often unavailable. In case of clinical cure (absence

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  • Efficacy of Single-Dose and Triple-Dose Albendazole and ...

    2020-10-16 · controlled single-dose drug efficacy trials pointed to a marked superiority of albendazole over mebendazole against hookworm, high efficacy (in terms of cure rate [CR]) of both drugs against A. lumbricoides, and disappointing efficacy of either drug against T. trichiura [18]. Few data are available regarding ERRs.

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  • Efficacy and safety of albendazole and high-dose ...

    The combination of ivermectin (IVM) and albendazole (ALB) has shown significant improvements in efficacy. Methods: Safety and efficacy randomized controlled clinical trial comparing 3 experimental regimens against ALB monotherapy for the treatment of T. trichiura infections in northern Honduras. Infected children were randomized to one of the following treatments: (Arm 1) single-dose ALB 400 mg; (Arm 2) single-dose …

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  • Efficacy and Safety of Single and Double Doses of ...

    2011-5-10 · In this study, the cure rate was found to be 63% when a 7-day course of high dose albendazole was used. The efficacy of albendazole varied widely even when the same dose and duration of treatment was used.

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  • Efficacy and safety of single and double doses of ...

    Conclusion/significance: This study confirms that both a single, and a double dose of oral ivermectin taken two weeks apart, is more effective than a 7-day course of high dose albendazole for patients with chronic infection due to S. stercoralis. Double dose of ivermectin, taken two weeks apart, might be more effective than a single dose in patients with concomitant illness.

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  • Efficacy and safety of a single-dose veterinary ...

    Efficacy and safety of a single-dose veterinary preparation of ivermectin versus 7-day high-dose albendazole for chronic strongyloidiasis. Suputtamongkol Y (1), Kungpanichkul N, Silpasakorn S, Beeching NJ. Author information: (1)Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand. [email protected]

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  • Efficacy of single dose combinations of albendazole ...

    1998-1-1 · In a ‘blind’ trial on 50 male asymptomatic microfilaraemic subjects with Wuchereria bancrofti infection, the safety, tolerability and filaricidal efficacy of a single dose of albendazole (alb) 600 mg alone or in combination with ivermectin (iver) 400 μg/kg or diethylcarbamazine citrate (DEC) 6 mg/kg was compared with a single dose of the combination DEC 6 mg/kg and iver 400 μg/kg over a ...

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  • Efficacy and safety of a single-dose veterinary ...

    A prospective, randomised, open study compared a 7-day course of oral albendazole 800 mg daily with a single oral dose of the parenteral veterinary preparation of ivermectin in 42 Thai patients with chronic strongyloidiasis (21 in each group). The primary endpoints were relief of symptoms (if presen …

    Get Price
  • Table - Efficacy of High-Dose Albendazole with

    Efficacy of High-Dose Albendazole with Ivermectin for Treating Imported Loiasis, Italy Federico Gobbi , Dora Buonfrate, Francesca Tamarozzi, Monica Degani, Andrea Angheben, and Zeno Bisoffi

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  • Efficacy of High-Dose Albendazole with Ivermectin for ...

    2021-4-28 · Patients had microfilaremia 20,000/mL and were treated with high-dose albendazole for 28 days and a single dose of ivermectin. This combination might be an effective treatment option in nonendemic areas, when diethylcarbamazine, the drug of choice, is not available.

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  • Efficacy of albendazole against the whipworm trichuris ...

    To repeat the dose on 2 or 3 days would increase cost, reduce compliance and complicate management. Albendazole cannot be used in deworming programmes in South Africa because it is a Schedule 4 prescription medicine. De-scheduling is needed urgently, particularly because of high efficacy against hookworm in KwaZulu-Natal and neighbouring countries.

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  • Efficacy and safety of albendazole and high-dose ...

    Gabriela Matamoros, Ana Sánchez, José Antonio Gabrie, Marisa Juárez, Laura Ceballos, Andrés Escalada, Carol Rodríguez, Helena Martí-Soler, María Mercedes Rueda, Maritza Canales, Carlos Lanusse, Pamela Cajal, Luis Álvarez, Rubén O Cimino, Alejandro Krolewiecki, Efficacy and safety of albendazole and high-dose ivermectin co-administration in school-aged children infected with Trichuris ...

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  • Efficacy and safety of albendazole and high-dose ...

    2021-4-27 · Gabriela Matamoros, Ana Sánchez, José Antonio Gabrie, Marisa Juárez, Laura Ceballos, Andrés Escalada, Carol Rodríguez, Helena Martí-Soler, María Mercedes Rueda, Maritza Canales, Carlos Lanusse, Pamela Cajal, Luis Álvarez, Rubén O Cimino, Alejandro Krolewiecki, Efficacy and safety of albendazole and high-dose ivermectin co-administration in school-aged children infected with Trichuris ...

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  • Efficacy of High-Dose Albendazole with Ivermectin for ...

    Emerging Infectious Diseases (2019-08-01) . Efficacy of High-Dose Albendazole with Ivermectin for Treating Imported Loiasis, Italy

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  • Efficacy and safety of a single-dose veterinary ...

    1. Int J Antimicrob Agents. 2008 Jan;31(1):46-9. Epub 2007 Nov 26. Efficacy and safety of a single-dose veterinary preparation of ivermectin versus 7-day high-dose albendazole for chronic strongyloidiasis.

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  • Efficacy of single dose combinations of albendazole ...

    1998-1-1 · In a ‘blind’ trial on 50 male asymptomatic microfilaraemic subjects with Wuchereria bancrofti infection, the safety, tolerability and filaricidal efficacy of a single dose of albendazole (alb) 600 mg alone or in combination with ivermectin (iver) 400 μg/kg or diethylcarbamazine citrate (DEC) 6 mg/kg was compared with a single dose of the combination DEC 6 mg/kg and iver 400 μg/kg over a ...

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  • Efficacy of a single dose versus a multiple dose

    2020-5-27 · Ethiopia is a hotspot area for hookworm and other STH infections. School children are disproportionately affected by these parasites [6, 26].Mass drug administration for selected risk groups, such as children, using a single dose of albendazole or mebendazole is the mainstay for the control of STHs in Ethiopia [].However, there are recent reports which showed a reduction of the efficacy of the ...

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  • Efficacy and safety of a single-dose veterinary ...

    2008-1-1 · A prospective, randomised, open study compared a 7-day course of oral albendazole 800 mg daily with a single oral dose of the parenteral veterinary preparation of ivermectin in 42 Thai patients with chronic strongyloidiasis (21 in each group).The primary endpoints were relief of symptoms (if present) and clearance of Strongyloides larvae from faeces immediately after treatment and at follow-up ...

    Get Price
  • Table - Efficacy of High-Dose Albendazole with

    Efficacy of High-Dose Albendazole with Ivermectin for Treating Imported Loiasis, Italy Federico Gobbi , Dora Buonfrate, Francesca Tamarozzi, Monica Degani, Andrea Angheben, and Zeno Bisoffi

    Get Price
  • Efficacy and safety of albendazole and high-dose ...

    Gabriela Matamoros, Ana Sánchez, José Antonio Gabrie, Marisa Juárez, Laura Ceballos, Andrés Escalada, Carol Rodríguez, Helena Martí-Soler, María Mercedes Rueda, Maritza Canales, Carlos Lanusse, Pamela Cajal, Luis Álvarez, Rubén O Cimino, Alejandro Krolewiecki, Efficacy and safety of albendazole and high-dose ivermectin co-administration in school-aged children infected with Trichuris ...

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  • Efficacy and safety of albendazole and high-dose ...

    2021-4-27 · Gabriela Matamoros, Ana Sánchez, José Antonio Gabrie, Marisa Juárez, Laura Ceballos, Andrés Escalada, Carol Rodríguez, Helena Martí-Soler, María Mercedes Rueda, Maritza Canales, Carlos Lanusse, Pamela Cajal, Luis Álvarez, Rubén O Cimino, Alejandro Krolewiecki, Efficacy and safety of albendazole and high-dose ivermectin co-administration in school-aged children infected with Trichuris ...

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  • A Randomized Controlled Trial of Increased Dose and ...

    2015-3-17 · At 12 months, Mf clearance was marginally greater with the high dose regimens, while by 24 months, there was a trend to higher Mf clearance in the arm with increased frequency and 800mg of albendazole (76.9%) compared to other arms, (S1:64%, S2:69.2% & H1:73.1%).

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  • Efficacy of co‐administration of albendazole and ...

    2002-5-28 · High cure rates and egg reduction rates of Ascaris and hookworm infection with a single dose of ALB have been reported in many studies (1; 22). As far as trichuriasis is concerned, both treatment regimens, viz. DEC + ALB and DEC alone produced very similar cure rates (81.6% vs . 77.3%) and almost the same egg reduction rates (84.0% vs . 85.6%).

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  • Efficacy and Safety of a Single Dose versus a Multiple ...

    A prospective, randomised, open study compared a 7-day course of oral albendazole 800 mg daily with a single oral dose of the parenteral veterinary preparation of ivermectin in 42 Thai patients with chronic strongyloidiasis (21 in each group).The primary endpoints were relief of symptoms (if present) and clearance of Strongyloides larvae from faeces immediately after treatment and at follow-up ...

    Get Price
  • Efficacy and safety of a single-dose veterinary ...

    2001-5-1 · TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE (2001) 95, 332-335 Long-term efficacy of single-dose combinations of albendazole, ivermectin and diethylcarbamazine for the treatment of bancroftian filariasis M. M. IsmaiT, R. L. Jayakody1, G. J. Weil2, Deepika Fernando1, M. S. G. De Silva3, G. A. C. De Silva3 and W. K. Balasooriya3 'Faculty of …

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  • Long-term efficacy of single-dose combinations of ...

    Anaemia is a worldwide public health problem. In May 2002, the General Assembly of the UN (Reference Haines and Cassels 1) re-emphasised that control of nutritional anaemia should be one of the global development goals achieved in the early years of this millennium. Despite this goal, the global prevalence of anaemia has declined little in the past decade (Reference Kraemer and Zimmermann 2).

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  • Efficacy of High-Dose Albendazole with Ivermectin for ...

    2019-7-16 · In 2018, a patient with high microfilaremia was reported to be clear of infection after four 21-day courses of albendazole at a dose of 400 mg daily, followed by a single 150 µg/kg dose of ivermectin . We describe the outcomes of 16 cases of imported loiasis in Italy with high-dose albendazole for 28 days and a single dose of ivermectin.

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  • Efficacy and Safety of Albendazole in Hookworm

    2020-7-15 · Given the remarkable higher efficacy observed, increasing the dose of albendazole for adults targeted by community-based MDA may aid in the interruption of transmission. The estimated cost of one albendazole tablet is 0.018 with an additional 10% for overhead costs .

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  • EFFICACY OF ALBENDAZOLE AGAINST spp. - actavet.vfu.cz

    2013-12-17 · The efficacy of imidazole compounds. particularly in treating monieziosis in sheep. goats and cattle. has been studied recently. B au e r (1990) compared albendazole. oxfendazole, febantel and praziquantel in naturally infected sheep and found 10090 efficacy using albendazole in the dose of 3.8 mg per 1 kg of body weight and febantel

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  • Long-term efficacy of single-dose combinations of ...

    2001-5-1 · TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE (2001) 95, 332-335 Long-term efficacy of single-dose combinations of albendazole, ivermectin and diethylcarbamazine for the treatment of bancroftian filariasis M. M. IsmaiT, R. L. Jayakody1, G. J. Weil2, Deepika Fernando1, M. S. G. De Silva3, G. A. C. De Silva3 and W. K. Balasooriya3 'Faculty of …

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  • Treatment and prevention of trichuriasis: efficacy of ...

    2015-7-1 · communities. Moreover, albendazole is used in a deworming programme in KwaZulu-Natal, at a dose of400 mg stat, given once or twice a year depending on the health region in that province. In terms of diagnosis, infection by intestinal helminthiasis can be determined and monitored by simple, non-invasive, sustainable and cost effective methods.

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  • Tolerability and efficacy of single dose albendazole ...

    Background. The tolerability and efficacy of single dose albendazole (400 mg), diethylcarbamazine citrate (DEC) (6 mg/kg bodyweight) or co-administration of albendazole (400 mg) + DEC (6 mg/kg bodyweight) was studied in 54 asymptomatic Wuchereria bancrofti microfilaraemic volunteers in a double blind hospital-based clinical study.

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  • ARTICLES Randomised trial of albendazole and pyrantel in ...

    2012-11-24 · 3 days of albendazole 400 mg daily (high efficacy); one dose of albendazole 400 mg (moderate efficacy); one dose of pyrantel (pyrantel embonate) 11 mg/kg (low efficacy). Growth was monitored for 12 months. Analyses were by intention to treat. Findings113 (18%) children were lost to follow-up—34 from

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  • Efficacy, Safety, and Pharmacokinetics of

    2015-10-20 · The safety and efficacy of a single-dose triple-drug therapy of the antifilarial drugs diethylcarbamazine (DEC), ivermectin (IVM), and albendazole (ALB) for LF are unknown. Methods. We performed a pilot study to test the efficacy, safety, and pharmacokinetics of single-dose DEC, IVM, and ALB in Wuchereria bancrofti -infected Papua New Guineans.

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  • Efficacy and tolerability of treatment with single doses ...

    2017-8-7 · Lymphatic filariasis (LF) affects 73 countries, causes morbidity and impedes socioeconomic development. We had found no difference in safety and micro (Mf) and macro filarial action of single-dose diethylcarbamazine (DEC) and DEC + albendazole (ABZ) in an F01 study done in India (year 2000). There was a programmatic need to evaluate safety and efficacy of multiple annual treatments (F02 ...

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  • Efficacy of Higher Albendazole and Ivermectin Doses

    2010-10-4 · Albendazole and ivermectin are currently used in combination for annual mass treatment of lymphatic filariasis in Africa. Although the drugs have been donated, the cost of such programmes is very high and has proven to be a major impediment to the success of programmes in many countries with limited financial resources.

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  • Efficacy of single-dose and triple-dose albendazole

    2011-9-27 · However, a recent meta-analysis of randomized placebo-controlled single-dose drug efficacy trials pointed to a marked superiority of albendazole over mebendazole against hookworm, high efficacy (in terms of cure rate [CR]) of both drugs against A. lumbricoides, and disappointing efficacy of either drug against T. trichiura. Few data are ...

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  • Tolerability and efficacy of single dose albendazole ...

    Background. The tolerability and efficacy of single dose albendazole (400 mg), diethylcarbamazine citrate (DEC) (6 mg/kg bodyweight) or co-administration of albendazole (400 mg) + DEC (6 mg/kg bodyweight) was studied in 54 asymptomatic Wuchereria bancrofti microfilaraemic volunteers in a double blind hospital-based clinical study.

    Get Price
  • Treatment and prevention of trichuriasis: efficacy of ...

    2015-7-1 · communities. Moreover, albendazole is used in a deworming programme in KwaZulu-Natal, at a dose of400 mg stat, given once or twice a year depending on the health region in that province. In terms of diagnosis, infection by intestinal helminthiasis can be determined and monitored by simple, non-invasive, sustainable and cost effective methods.

    Get Price
  • Efficacy and tolerability of treatment with single doses ...

    2017-8-7 · Lymphatic filariasis (LF) affects 73 countries, causes morbidity and impedes socioeconomic development. We had found no difference in safety and micro (Mf) and macro filarial action of single-dose diethylcarbamazine (DEC) and DEC + albendazole (ABZ) in an F01 study done in India (year 2000). There was a programmatic need to evaluate safety and efficacy of multiple annual treatments (F02 ...

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  • ARTICLES Randomised trial of albendazole and pyrantel in ...

    2012-11-24 · 3 days of albendazole 400 mg daily (high efficacy); one dose of albendazole 400 mg (moderate efficacy); one dose of pyrantel (pyrantel embonate) 11 mg/kg (low efficacy). Growth was monitored for 12 months. Analyses were by intention to treat. Findings113 (18%) children were lost to follow-up—34 from

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  • Assessment of Anthelmintic Efficacy of Mebendazole

    Comparison of efficacy between a single dose of albendazole and mebendazole against hookworm infection. Forest plot comparing the anthelmintic drug efficacy measured by means of fecal egg reduction (FECR) rate of a single oral dose of 400 mg albendazole (ALB) and a single oral dose of 500 mg mebendazole (MEB) against hookworm infections.

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  • Evaluation of efficacy of school-based anthelmintic ...

    Cost-effectiveness analysis The cost per child treated was US 0.23 for albendazole and US 0.79 for praziquantel, i.e. US 1.02 per child treated with both drugs (14). This represents the price of the drug and all delivery costs including those of distribution, training, and prior screening for …

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  • Efficacy of High-Dose versus Standard-Dose Influenza ...

    The OXF dose of 30 mg/kg was selected on the basis of its efficacy against Taenia solium cysticercosis in pigs 13 and treatment of sheep for hydatid cysts. 4, 14 However, the 15 mg/kg BW dose of NTZ was selected on the basis of the highest described nontoxic dose used in humans 18 – 20 and a trial performed in pigs.

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  • CIENCIASMEDICASNEWS: Efficacy of High-Dose

    2021-7-5 · In 2018, a patient with high microfilaremia was reported to be clear of infection after four 21-day courses of albendazole at a dose of 400 mg daily, followed by a single 150 µg/kg dose of ivermectin . We describe the outcomes of 16 cases of imported loiasis in Italy with high-dose albendazole for 28 days and a single dose of ivermectin.

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  • Use of High-Dose, Twice-Yearly Albendazole and

    2010-12-1 · Study design. Eligible participants were randomly assigned to receive annual treatment with standard-dose albendazole (400 mg) and ivermectin (150 µg/kg) or twice-yearly treatment with high-dose albendazole (800 mg) and ivermectin (400 µg/kg) for 24 months (Figure 1).A brief clinical assessment, including vital signs and pregnancy testing (in women of childbearing age), was performed at each ...

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  • ARTICLES Randomised trial of albendazole and pyrantel in ...

    2012-11-24 · 3 days of albendazole 400 mg daily (high efficacy); one dose of albendazole 400 mg (moderate efficacy); one dose of pyrantel (pyrantel embonate) 11 mg/kg (low efficacy). Growth was monitored for 12 months. Analyses were by intention to treat. Findings113 (18%) children were lost to follow-up—34 from

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  • Comparative efficacy and safety of topical permethrin ...

    Efficacy and safety of single and double doses of ivermectin versus 7-day high dose albendazole for chronic strongyloidiasis Y Suputtamongkol, N Premasathian, K Bhumimuang, D Waywa, S Nilganuwong, E Karuphong, T Anekthananon, D Wanachiwanawin, S Silpasakorn

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  • Efficacy and safety of single and double doses of ...

    2011-5-31 · Suputtamongkol Y, Premasathian N, Bhumimuang K, Waywa D, Nilganuwong S, et al. PLoS Negl Trop Dis 2011 5: e1044. A prospective, randomized, open study was conducted in which a 7-day course of oral albendazole 800 mg daily was compared with a single dose (200 microgram/kilogram body weight) or double doses, given 2 weeks apart, of ivermectin in Thai patients with chronic strongyloidiasis.

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  • Use of High-Dose, Twice-Yearly Albendazole and

    2010-12-1 · Clearance of microfilaremia after high-dose, twice-yearly albendazole and ivermectin, compared with standard-dose annual treatment. The bars represent the percentage of patients with detectable Wuchereria bancrofti microfilariae at baseline and 6, 12, 18, and 24 months after treatment.

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  • Systematic review of the effectiveness of selected

    2020-1-16 · Results. We identified 3555 records, of which we included 20 primary studies reported across 33 articles. Meta-analyses of drug and dose showed that a single dose of praziquantel 10mg/kg, albendazole 400mg per day for three consecutive days, or niclosamide 2g, resulted in better cure rates for T.solium taeniasis (99.5%, 96.4% and 84.3%, respectively) than praziquantel 5mg/kg or single dose ...

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  • The efficacy of a slow-release albendazole capsule against ...

    2015-1-31 · first study to report on the efficacy of such products under South African field conditions in sheep harbouring a population of Haemonchus contortus with known multiple anthelmintic resistance, including to albendazole. Treatment groups were comprised of CRC-treated and single dose albendazole-treated sheep, as well as negative controls.

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  • Efficacy of High-Dose versus Standard-Dose Influenza ...

    2016-9-20 · established a target LED package efficacy of 266 lm/W, with LED luminaire efficacy exceeding 200 lm/W.2 Upon reaching such levels, LEDs would far surpass the efficacy of current linear fluorescent, compact fluorescent, high intensity discharge (HID), and incandescent sources, all of which are generally considered

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  • Efficacy of Higher Albendazole and Ivermectin Doses

    2010-10-4 · Albendazole and ivermectin are currently used in combination for annual mass treatment of lymphatic filariasis in Africa. Although the drugs have been donated, the cost of such programmes is very high and has proven to be a major impediment to the success of programmes in many countries with limited financial resources.

    Get Price
  • (PDF) Efficacy of albendazole against the whipworm ...

    Single-dose treatments are optimal in research shows that in 2003, albendazole and mebendazole terms of management and cost, with albendazole 400 mg purchased in Europe or Asia could be delivered to schools in tablets being one option.6-14 However, Trichuris is relatively Cape Town for about 20% of the government’s tender prices for ...

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  • Treatment and prevention of trichuriasis : efficacy of ...

    Moreover, albendazole is used in a deworming programme in KwaZulu-Natal, at a dose o f400 mg stat, given once or twice a year depending on the health region in that province. In terms of diagnosis, infection by intestinal helminthiasis can be determined and monitored by simple, non-invasive, sustainable and cost effective methods.

    Get Price
  • Assessment of Anthelmintic Efficacy of Mebendazole

    Comparison of efficacy between a single dose of albendazole and mebendazole against hookworm infection. Forest plot comparing the anthelmintic drug efficacy measured by means of fecal egg reduction (FECR) rate of a single oral dose of 400 mg albendazole (ALB) and a single oral dose of 500 mg mebendazole (MEB) against hookworm infections.

    Get Price
  • Systematic review of the effectiveness of selected

    2020-1-16 · Results. We identified 3555 records, of which we included 20 primary studies reported across 33 articles. Meta-analyses of drug and dose showed that a single dose of praziquantel 10mg/kg, albendazole 400mg per day for three consecutive days, or niclosamide 2g, resulted in better cure rates for T.solium taeniasis (99.5%, 96.4% and 84.3%, respectively) than praziquantel 5mg/kg or single dose ...

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  • Assessment of Anthelmintic Efficacy of Mebendazole

    2014-10-9 · Author Summary Soil-transmitted helminths (STHs; roundworms, whipworms, and hookworms) infect millions of children in sub-tropical and tropical countries, resulting in malnutrition, growth stunting, intellectual retardation, and cognitive deficits. To fight against STH, large-scale deworming programs are implemented in which anthelmintic drugs (either albendazole (ALB) or …

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  • Tolerability and efficacy of single dose albendazole ...

    2002-10-10 · The tolerability and efficacy of single dose albendazole (400 mg), diethylcarbamazine citrate (DEC) (6 mg/kg bodyweight) or co-administration of albendazole (400 mg) + DEC (6 mg/kg bodyweight) was studied in 54 asymptomatic Wuchereria bancrofti microfilaraemic volunteers in a double blind hospital-based clinical study. There was no significant difference in the overall incidence of adverse ...

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  • THE LANCET Randomised placebo-controlled comparison

    2012-11-24 · evidence on whether single-dose albendazole is effective against W bancrofti, a macrofilaricidal effect has been reported in men given daily doses of 800 mg for 3 weeks.13 The efficacy of ivermectin and albendazole given together in a single dose,and the frequency and severity of adverse reactions, are unknown.Therefore,

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  • Effectiveness of Deworming with Single-Dose

    2021-3-19 · Children received 1 dose of albendazole (400 mg, per WHO guidelines) on enrollment. 1 Albendazole was administered under direct observation by a clinic nurse. Metronidazole was prescribed for any child with amoebiasis (35 mg/kg/day every 8 hours for 7 days) or giardiasis (25 mg/kg/day every 8 hours for 5 days) at any time point.

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  • Evaluation of Nitazoxanide and Oxfendazole Efficacy ...

    The OXF dose of 30 mg/kg was selected on the basis of its efficacy against Taenia solium cysticercosis in pigs 13 and treatment of sheep for hydatid cysts. 4, 14 However, the 15 mg/kg BW dose of NTZ was selected on the basis of the highest described nontoxic dose used in humans 18 – 20 and a trial performed in pigs.

    Get Price
  • Efficacy of Higher Albendazole and Ivermectin Doses

    2010-10-4 · Albendazole and ivermectin are currently used in combination for annual mass treatment of lymphatic filariasis in Africa. Although the drugs have been donated, the cost of such programmes is very high and has proven to be a major impediment to the success of programmes in many countries with limited financial resources.

    Get Price
  • Effectiveness of Deworming with Single-Dose

    2021-3-19 · Children received 1 dose of albendazole (400 mg, per WHO guidelines) on enrollment. 1 Albendazole was administered under direct observation by a clinic nurse. Metronidazole was prescribed for any child with amoebiasis (35 mg/kg/day every 8 hours for 7 days) or giardiasis (25 mg/kg/day every 8 hours for 5 days) at any time point.

    Get Price
  • [PDF] Analysis of efficacy and cost-effectiveness of

    High-dose arabinoside (HiDAC) and daunorubicin (DNR)-based chemotherapy are the primary consolidation treatment options for older adults (50–60 years old) with acute myeloid leukemia in China. We analyzed the event-free survival (EFS) and hospital treatment charges of older adult patients with different cytogenetic risk profiles. In patients with a better/intermediate risk profile, the ...

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  • A Prospective Randomized Study of the Efficacy and Cost ...

    2011-8-9 · Objective: To compare the efficacy and cost-effectiveness of high and low dose regimens of I-131 treatment in patients with hyperthyroidism. Material and Method: One hundred fifty patients with proven hyperthyroidism were randomly allocated into the high (74 patients) and low (76 patients) dose regimen of I-131 treatment.

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  • Update on Treatment and Resistance of Human Trichuriasis

    2017-8-27 · The choice of albendazole is based on its cost-effectiveness, safety and logistical advantages as a single- ... the dose of albendazole even when administered as a single dose also led to higher CR (43.4 % [32.2–54.6 %]) [46†] ... Thus, Curr Trop Med Rep (2015) 2:218–223 219. efficacy of albendazole is dependent on the dose and the length ...

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  • Control programs for strongyloidiasis in areas of high ...

    2021-5-25 · Speich B, Ali SM, Ame SM, Bogoch II, Alles R, Huwyler J, et al. Efficacy and safety of albendazole plus ivermectin, albendazole plus mebendazole, albendazole plus oxantel pamoate, and mebendazole alone against Trichuris trichiura and concomitant soil-transmitted helminth infections: a four-arm, randomised controlled trial. Lancet Infect Dis ...

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  • Improvement in the efficacy of existing combination of ...

    The DEC-albendazole combination shows efficacy close to the DEC-ivermectin combination in terms of micro filarial (Table 1) as well as adult worm killing (Figure 1), the combination preferred in India over DEC-ivermectin because of its cost-effectiveness, easy availability of alben dazole and its additional effect on intestinal parasites16.

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  • High Dose Influenza Vaccine for Adults: A Review of ...

    this report, there was only one high-dose formulation approved in Canada, the intra-muscular Fluzone® High-Dose influenza vaccine, a trivalent formulation with 60µg of hemagglutinin (HA) in a 0.5mL dose;1 this is compared to the standard dose of vaccine, which is ordinarily 15µg HA in 0.5mL. High-dose vaccine is indicated for use in adults aged

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  • Efficacy of the cyclooctadepsipeptide PF1022A against ...

    A moderate, non-significant worm burden reduction was achieved, when a single oral dose of 10 mg/kg albendazole was given to H. bakeri-infected mice (ED 50 of albendazole 9·8 mg/kg ). Table 4. In vivo efficacy of PF1022A, ivermectin levamisole and albendazole and combinations of PF1022A and ivermectin, PF1022A and levamisole, and PF1022A and ...

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  • Efficacy and Safety of Albendazole in Hookworm

    Given the remarkable higher efficacy observed, increasing the dose of albendazole for adults targeted by community-based MDA may aid in the interruption of transmission. The estimated cost of one albendazole tablet is 0.018 with an additional 10% for overhead costs .

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  • Evaluation of efficacy of school-based anthelmintic ...

    Cost-effectiveness analysis The cost per child treated was US 0.23 for albendazole and US 0.79 for praziquantel, i.e. US 1.02 per child treated with both drugs (14). This represents the price of the drug and all delivery costs including those of distribution, training, and prior screening for …

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  • Improvement in the efficacy of existing combination of ...

    The DEC-albendazole combination shows efficacy close to the DEC-ivermectin combination in terms of micro filarial (Table 1) as well as adult worm killing (Figure 1), the combination preferred in India over DEC-ivermectin because of its cost-effectiveness, easy availability of alben dazole and its additional effect on intestinal parasites16.

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  • [PDF] Analysis of efficacy and cost-effectiveness of

    High-dose arabinoside (HiDAC) and daunorubicin (DNR)-based chemotherapy are the primary consolidation treatment options for older adults (50–60 years old) with acute myeloid leukemia in China. We analyzed the event-free survival (EFS) and hospital treatment charges of older adult patients with different cytogenetic risk profiles. In patients with a better/intermediate risk profile, the ...

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  • Efficacy of the cyclooctadepsipeptide PF1022A against ...

    A moderate, non-significant worm burden reduction was achieved, when a single oral dose of 10 mg/kg albendazole was given to H. bakeri-infected mice (ED 50 of albendazole 9·8 mg/kg ). Table 4. In vivo efficacy of PF1022A, ivermectin levamisole and albendazole and combinations of PF1022A and ivermectin, PF1022A and levamisole, and PF1022A and ...

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  • Efficacy and safety of ivermectin and albendazole co ...

    2019-3-18 · Soil-transmitted helminthiasis affects almost 2 billion people worldwide in tropical climates. Preventive chemotherapy, using the benzimidazoles (albendazole and mebendazole) is the current main recommended control strategy. Nevertheless, there is limited efficacy of these drugs against hookworm infection and, to a greater extent, against trichuriasis.

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  • Efficacy and Safety of a Single-Dose Mebendazole 500

    2017-9-5 · Efficacy of single-dose and triple-dose albendazole and mebendazole against soil-transmitted helminths and Taenia spp.: a randomized controlled trial. PLoS One 6 : e25003 . Steinmann P Utzinger J Du Z-W Jiang J-Y Chen J-X Hattendorf J Zhou H Zhou X-N , 2011 .

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  • Efficacy of Current Drugs Against Soil-Transmitted ...

    Efficacy of a single dose albendazole chemotherapy on human intestinal helminthiasis among school children in selected rural tropical communities. Joseph Eyo. Related Papers. Effects of Annual Mass Treatment with Ivermectin for Onchocerciasis on the Prevalence of Intestinal Helminths.

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  • (PDF) Efficacy of a single dose albendazole

    Two doses of artesunate were more cost-effective compared to single-dose PZQ . Nonetheless, PZQ-artesunate combination was safer and more effective as opposed to using either drug [ 24 , 25 ]. Metrifonate, a cholinesterase inhibitor, is another selective treatment for SH; it has good efficacy and safety profiles [ 26 ].

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  • [PDF] Analysis of efficacy and cost-effectiveness of

    High-dose arabinoside (HiDAC) and daunorubicin (DNR)-based chemotherapy are the primary consolidation treatment options for older adults (50–60 years old) with acute myeloid leukemia in China. We analyzed the event-free survival (EFS) and hospital treatment charges of older adult patients with different cytogenetic risk profiles. In patients with a better/intermediate risk profile, the ...

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  • The Effect of Drug Pricing on Outpatient Payments

    2011-8-9 · Objective: To compare the efficacy and cost-effectiveness of high and low dose regimens of I-131 treatment in patients with hyperthyroidism. Material and Method: One hundred fifty patients with proven hyperthyroidism were randomly allocated into the high (74 patients) and low (76 patients) dose regimen of I-131 treatment.

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  • A Prospective Randomized Study of the Efficacy and Cost ...

    Efficacy and safety of a single-dose veterinary preparation of ivermectin versus 7-day high-dose albendazole for chronic strongyloidiasis select distinct n.content as name, r.content as role, t.nameID as nameID, n.unitID as unitID, n.departmentID as departmentID, n ...

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  • Efficacy and safety of a single-dose veterinary

    A moderate, non-significant worm burden reduction was achieved, when a single oral dose of 10 mg/kg albendazole was given to H. bakeri-infected mice (ED 50 of albendazole 9·8 mg/kg ). Table 4. In vivo efficacy of PF1022A, ivermectin levamisole and albendazole and combinations of PF1022A and ivermectin, PF1022A and levamisole, and PF1022A and ...

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  • Efficacy of the cyclooctadepsipeptide PF1022A against ...

    2008-6-15 · An adequate response to this new challenge was urgently needed. A meeting on 'Monitoring of drug efficacy in large scale treatment programmes in human helminthiasis', jointly organized by WHO and the World Bank, took place in Washington, DC at the World Bank Headquarters from 31 October to 2 November 2007, with the aim of addressing the issue ...

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  • Monitoring of drug efficacy in large scale treatment ...

    this report, there was only one high-dose formulation approved in Canada, the intra-muscular Fluzone® High-Dose influenza vaccine, a trivalent formulation with 60µg of hemagglutinin (HA) in a 0.5mL dose;1 this is compared to the standard dose of vaccine, which is ordinarily 15µg HA in 0.5mL. High-dose vaccine is indicated for use in adults aged

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  • High Dose Influenza Vaccine for Adults: A Review of ...

    2015-5-27 · The aims of this study were to compare the pharmacokinetics of albendazole sulfoxide (ABZ-SO, ricobendazole) in goats and sheep at a dose of 5 mg/kg bodyweight (BW), after intravenous (IV) and subcutaneous (SC) administrations, and to investigate the effects of increased doses (10 and 15 mg/kg BW) on the plasma disposition of ABZ-SO in goats following SC administration.

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  • Comparative pharmacokinetics and bioavailability of ...

    2020-10-20 · In contrast, oxfendazole is more soluble and reaches higher plasma concentrations compared to fenbendazole and albendazole after a single dose (Gokbulut et al., 2007). Not only is oxfendazole more effective, but it was also shown to reach 100% FECR much sooner than did fenbendazole (day 12 vs. day 31) in a study comparing the efficacy of these ...

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