Sulfamethoxazole-Trimethoprim Treatment of Guinea
Sulfamethoxazole-trimethoprim levels. Sixteen unin-fected guinea pigs received five doses of either high-dose or low-dose sulfamethoxazole-trimethoprim. Two animals in each group were killed by exsanguination at 1, 2, 6, and 12 hr after the fifth dose. Serum levels of sulfamethoxa-zole and trimethoprim were measured by Dr. H. Spiegel
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