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    2021-1-21 · What is tilmicosin? 1. Definition. Tilmicosin is an over-the-counter drug. It is a semi-synthesized livestock and poultry antibiotic from a hydrolysate of tylosin, and tilmicosin phosphate is used for medicine. It is mainly used to prevent and treat domestic animal pneumonia (caused by infection of Actinobacillus pleuropneumoniae, Pasteurella ...

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    Mark G. Papich DVM, MS, DACVCP, in Saunders Handbook of Veterinary Drugs (Fourth Edition), 2016 Pharmacology and mechanism of action. Tildipirosin is an antibacterial of the macrolide class. It is a 16-membered ring (tilmicosin also is a 16-member ring molecule) macrolide antimicrobial with three charged nitrogen atoms (tulathromycin also has 3 charged nitrogen atoms).

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    2019-5-25 · A high-performance liquid chromatography (HPLC) method with detection at 290 nm was modified and validated for the determination of tilmicosin residues in broiler chicken tissues. The limits of detection (LOD) of the method were 0.01 μg/g for muscle and 0.025 μg/g for liver and kidney. Average recoveries ranged from 80.4 to 88.3%. Relative standard deviation values ranged from 5.2 to 12.1% ...

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    2019-10-7 · Tilmicosin, 20–deoxo–20-(3,5-dimethylpiperidin-l-yl) desmycosin, a synthetic derivative of tylosin, is a macrolide antibiotic for livestock and poultry (Debono et al., 1989). It has a similar molecular structure and antibacterial spectrum to tylosin (Kirst et al., 1989 ).

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    Affiliations 1 National Reference Laboratory of Veterinary Drug Residues (H.Z.A.U.) and MAO Key Laboratory for Detection of Veterinary Drug Residues, Wuhan 430070, China.; 2 MOA Laboratory for Risk Assessment of Quality and Safety of Livestock and Poultry Products, Huazhong Agricultural University, Wuhan 430070, China.; 3 Department of Clinical Pathology, Faculty of Veterinary Medicine, Benha ...

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    2018-4-3 · Some commonly used brand names are: For veterinary-labeled products— Draxxin [Tulathromycin] Pulmotil Premix [Tilmicosin Phosphate] Erythro-200 [Erythromycin Base] Tylan 10 [Tylosin Phosphate] Erythro-Med [Erythromycin Phosphate] Tylan 40 [Tylosin Phosphate] Gallimycin [Erythromycin Phosphate]

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    2018-4-3 · Description. A macrolide antibiotic recommended for treatment and prevention of pneumonia associated with Pasteurella haemolytica, P. multocida, Actinobacillus pleuropneumoniae, mycoplasma species and other microorganisms. Availability status. -. Introduction & key dates. -. …

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    losin, is a macrolide antibiotic for livestock and poultry (Debono et al., 1989). It has a similar molecular structure and antibacterial spectrum to tylosin (Kirst et al., 1989). According to research, tilmicosin has a good inhibitory effect on Gram-positive bacteria and some …

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    A bioavailability and pharmacokinetics study of powder and liquid tilmicosin formulations was carried out in 18 healthy chickens according to a single-dose, two-period, two-sequence, crossover randomized design. The two formulations were Provitil and Pulmotil AC. Both drugs were administered to each chicken after an overnight fast on two treatment days separated by a 2-week washout period.

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    2008-12-1 · Tilmicosin is a macrolide antibiotic chemically synthesized from tylosin, with antimicrobial activity against Gram positive anaerobic bacteria, Mycoplasma spp., and Gram negative respiratory pathogens including Mannheimia haemolytica and Pasteurella multocida . Desirable pharmacokinetic properties of tilmicosin include rapid absorption following oral administration, good penetration of ...

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